Necrotising lymphadenitis without granulocytic infiltration (Kikuchi's disease)

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Necrotising lymphadenitis without granulocytic infiltration (Kikuchi's disease).

Kikuchi's disease (necrotising lymphadenitis) is characterised by cervical lymphadenopathy in young patients and may be mistaken for malignant disease both clinically and histologically. Microscopically, there is a varying degree of effacement of the lymph node architecture and necrosis with an infiltrate of "histiocytic" cells and absence of polymorphs. The disease is of unknown aetiology. It ...

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( Kikuchi ' s disease ) without granulocytic infiltration Necrotising lymphadenitis

' Martuza RL, Miller DC, MacLoughlin DT. Estrogen and progestin binding by cytosolic and nuclear fractions of human meningiomas. J Neurosurg 1985;62:750-6. 2Van Netten JP, Algard FT, Coy P, et al. Estrogen receptor assay on breast cancer microsamples. Implications of percent carcinoma estimation. Cancer 1982;49:2383-8. 3Ironside JW, Battersby RDE, Dangerfield VJM, Parsons MA, Timperley WR, Unde...

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Histiocytic Necrotising Lymphadenitis

s: Background: Kikuchi’s disease is a rare, benign, self-limiting disease, mainly involving the lymph nodes of young people. The disease has unknown etiology. Clinical symptoms and basic investigations in a patient often leads to a misdiagnosis, due to similar findings in other lesions like, lymphomas and chronic granulomatous inflammations of lymph nodes like tuberculosis. Lymph node biopsy sh...

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Histiocytic necrotising lymphadenitis in systemic lupus erythematosus.

Histiocytic necrotising lymphadenitis is the pathognomonic histological appearance of lymph nodes in Kikuchi's disease, a condition characterised by a brief systemic illness and lymphadenopathy. The case is described of a young man, originally diagnosed as having Kikuchi's disease by lymph node histology, who subsequently developed systemic lupus erythematosus with symmetrical polyarthritis, Co...

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Kikuchi-Fugimoto Disease (Cervical Subacute Necrotising Lymphadenitis): An important benign disease often masquerading as lymphoma

OBJECTIVES We describe a rare cause of posterior triangle cervical lymphadenopathy in a third decade female, outline the clinical and histopathological features and discuss excision biopsy as the investigation of choice in this age group, with lymphoma as the diagnosis of exclusion. CASE REPORT A thirty-four year old female was referred to our Head and Neck clinic with a one-month history of ...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1986

ISSN: 0021-9746

DOI: 10.1136/jcp.39.7.811-c